DNA甲基化与癌症、泛癌早筛 | DNA methylation and pan-cancer

虽然我们现在完全没有甲基化的数据,但还是可以了解一下。

什么是DNA甲基化,与组蛋白修饰有什么联系?

DNA Methylation and Its Basic Function

表观的定义就是DNA序列不变、表型变了。最重要的就是DNA的修饰(甲基化)和组蛋白的修饰(chip-seq里面的那几种)

为什么说甲基化比SNP在早筛方面要靠谱得多?

Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors

New England Biolabs® Launches NEBNext® Enzymatic Methyl-seq (EM-seq™) for Bisulfite-Free Methylation Analysis
This new enzyme-based system allows scientists to accurately and sensitively assess DNA methylation without bisulfite treatment, for epigenetics research.
亚硫酸氢盐很快将成为过去时

参考:

华大基因发布多项肿瘤早筛新技术 从血液中捕捉癌细胞信号

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转载自www.cnblogs.com/leezx/p/10802653.html
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