参考基因组下载

参考http://www.biotrainee.com/thread-1835-1-1.html

hg19.fa在2.98G左右，压缩文件800-900Mb

//chromFa.tar.gz

cd ~/reference

mkdir -p genome/hg19  && cd genome/hg19

nohup wget http://hgdownload.cse.ucsc.edu/goldenPath/hg19/bigZips/chromFa.tar.gz &

tar zvfx chromFa.tar.gz

cat *.fa > hg19.fa

rm chr*.fa

//hg19.2bit

wget http://hgdownload.cse.ucsc.edu/goldenPath/hg19/bigZips/hg19.2bit

twoBitToFa hg19.2bit hg19.fa

head hg19.fa

可能在着丝粒或者没测出来,占总基因组105左右，继续看下去是正常的ATCG