Table 2. Comparison of different microRNA–disease relationship
prediction method
Type Method Reference
Local Boolean network [16]
KNN [21, 22]
Global Random Walk [23, 24]
Semi-supervised learning [54, 55]
Table 3. The Web Source for miRNA–disease relationship research
Name Website Reference Annotation
HDMP http://nclab.hit.edu.cn/hdmpred/ [21] Human disease-related miRNA prediction
HMDD2.0 http://www.cuilab.cn/hmdd [8] Human miRNA disease database
miR2Disease http://www.mir2disease.org/ [7] miRNA-disease relationship database
Misim http://www.cuilab.cn/files/images/cuilab/misim.zip [57] A tool for the miRNA functional similarity measuring and network construction
SmiRFN http://nclab.hit.edu.cn/SoymiRNet/ [14] Soybean microRNA functional network