What are the potential new drugs in 2023? This is a question with infinite possibilities and unknown challenges. The research and development of new drugs is the goal that pharmaceutical companies are constantly pursuing. Every success can bring huge profits, improve the quality of life of patients, and achieve the company's reputation. But at the same time, the risk of new drug research and development is also extremely high, the project failure rate is high, the cycle is long, and the investment is huge. Therefore, how to identify and develop innovative drugs with excellent quality has become a topic that pharmaceutical companies need to constantly think about and practice.
The competitiveness of the pharmaceutical industry comes not only from the quantity of drugs, but more importantly, the quality and innovation of new drugs. The conditions that a good innovative drug needs to meet include: significant curative effect, good safety and tolerability, good pharmacokinetics and pharmacokinetic properties, and reasonable price. Therefore, when pharmaceutical companies decide which drug R&D projects to invest in, they often consider the following aspects:
1. Pharmaceutical technology and market trends
Pharmaceutical technology is not only a long-cherished wish within pharmaceutical companies, but also a field closely related to industries such as big data, the Internet, and intelligence. Can breakthroughs in pharmaceutical technology improve pharmaceutical efficiency and industrial level, thereby helping the company develop some medical molecules and advanced testing equipment, and thus form the company's strong competitiveness in the market. Predicting market trends is also something pharmaceutical companies must consider. If the company can discover a new way to save lives, then its market prospects are undoubtedly very good, and the company's research and development investment may also have a high return. Therefore, having a clear understanding of pharmaceutical technology and market trends is the basis for corporate decision-making.
2. Identify medical value and clinical data
Each new drug must go through a series of clinical trials to ensure its effectiveness and safety. In order to reduce risks, pharmaceutical companies need to choose drug research projects based on medical value theory. Medical value refers to the effect of a drug in treating a certain disease, and evaluates whether its therapeutic effect meets the needs of patients. Clinical data is an important product of evaluating the results of medical trials, which reflects the safety and effectiveness data of this drug. Pharmaceutical companies use mathematical models and data analysis to help them decide whether to proceed with R&D projects. Typically, pharmaceutical companies need to create an overall value proposition for developing an entire drug portfolio.
3. Evaluate team background and funding
Team background is one of the important factors in evaluating the quality of medicines. Pharmaceutical companies must consider who can successfully develop a particular drug. Therefore, pharmaceutical companies need to assess the background of the team and let the talents lead the innovation. Especially in the field of human medicine, companies need to have both a scientific research foundation and a good level of management, preferably a solid financial reserve. Such as pharmaceutical companies. The amount and efficiency of use of funds determine the extent and speed of enterprise development.
4. Learn from the efficacy of existing drugs
In addition to their own medicines, pharmaceutical companies also need to regularly conduct research on approved drugs and therapies and compare them with their competitive advantages. This approach helps companies discover the unique characteristics of human medicines and the advantages they can draw on in the development of new medicines. These experiences can help companies determine whether the drugs they develop have advantages over existing products.
The above are the elements that pharmaceutical companies need to consider when making decisions. Therefore, we can analyze which drugs are available based on these elements,
It can also be based on the publicly-reviewed drugs of various countries and combined with the Chinese market as a reference. For example, the UK in the European Union has rated dozens of innovative drugs with potential. Below, the author will check through the Yaorong Cloud-Global Drug R&D Database.
First, log in to the enterprise version of the drug Rongyun database --> select 'Drug R&D' --> select 'Global Drug R&D' --> find 'Special Approval' and select 'Potential Innovative Drugs' --> click 'Search'
You can see the search results as shown in the figure below. There are 55 innovative drugs with potential in the public evaluation of the European Union and the United Kingdom. The potential innovative drugs can be discovered through comparative analysis of domestic and foreign listing conditions and sales conditions at home and abroad.
Screenshot Source: Yaorong Cloud - Global Drug R&D Database
In addition to screening potential innovative drugs, you can also check the latest active substances, Japan's Sakigake plan and other instructive drugs.
The following is part of the data derived by the author, you can refer to the research yourself
