As we all know, the methods used to diagnose COVID-19 at this stage include nucleic acid detection and IgG/IgE antibody detection. The establishment of rapid and accurate specific detection methods is of great significance to the control of the epidemic. Antigen and antibody detection reagents may achieve high throughput of the virus. Screening. The next thing to share is antigen testing.
Antigen testing can detect various types of samples to find protein molecules on the surface of the virus. This method can get results faster. It can also conduct preliminary rapid screening of COVID-19 in various samples. Speaking of this, Some of the friends may have guessed that Xiao Ai has brought you good products again. That's right, here Xiao Ai wants to introduce to you a simple, fast and cost-effective COVID-19 brand from the agency brand Abbexa we just signed. Antigen detection kit.
1. The testing process of the kit
2. Operation method of COVID-19 antigen detection kit
Abbexa's COVID-19 antigen rapid detection kit is a qualitative lateral flow immunochromatographic analysis method, mainly used to detect SARS-CoV-2 antigen in human pharynx, nose and nasopharyngeal swabs.
The box contains a monoclonal antibody against SARS-CoV-2 / COVID-19. The capture antibody is coupled with gold-labeled nanoparticles to capture any SARS-CoV-2 antigen present in the sample. SARS-CoV-2 specific monoclonal antibody (detection antibody) is coated in the detection area on the nitrocellulose membrane. The antibody binds to the previously formed antigen-antibody complex and forms a strip of color due to the gold nanoparticles. The inspection line and the quality control area at the top of the cassette can confirm whether the inspection is successful.
3. How long will the results be available?
Within 10 minutes.
4. How to interpret the results?
When reading, 1 line of color should be displayed in the C area (quality control area), the purple line next to the T area (test area) indicates a positive result, and a light line is also regarded as a positive result.
1. C and T areas are positive: the user has been infected or re-infected by the coronavirus most recently.
2. Positive in C zone and negative in T zone: The user has not been infected with coronavirus, or has been infected as recently as possible and has not provided enough antigen.
3. C zone negative, T zone positive or negative: the test is invalid, please use a new cassette to retest.
If the test result is negative:
1. May not have encountered the virus, or encountered the virus only recently, and there is not enough antigen to be detected by the rapid test kit.
2. If necessary, nucleic acid testing can be performed to assist in confirming whether the virus has been infected.
COVID-19 antigen detection kit details
Five, specificity and sensitivity
Sensitivity and specificity of the COVID-19 antigen rapid test kit (article number: abx294181): 31 swab samples that were positive for SARS-CoV-2 infection by RT-PCR were selected, and among the swab samples that were negative 127 samples were selected and tested with the COVID-19 antigen rapid test kit (abx294181). Of the 31 PCR positive samples, abx294181 showed that 28 were positive, and out of 127 PCR negative samples, abx294181 showed that 126 were positive. Negative.
Sensitivity: 28/31=90.32%
Specificity: 126/127=99.21%
Cross-reaction detection:
The kit has been verified to have no cross-reactivity with the following pathogens:
COVID-19 antigen rapid test kit link:
https://www.amyjet.com/brand/Abbexa.shtml