① whl download files in the library jpyre1 unofficial python library website
https://www.lfd.uci.edu/~gohlke/pythonlibs
Cp behind the figures represent the python version is 3.5 so I downloaded ad3-2.2.1-cp35-cp35m-win_amd64.whl.
②pip install ad3-2.2.1-cp35-cp35m-win_amd64.whl to OK!