A little question about oracle time conversion

select rownum ro,
       q.what_id,
       q.lib_id,
       q.que_code,
       q.type_code,
       q.base_code,
       q.diff_code,
       q.knowledge_id,
       q.ability_code,
       q.create_user,
       q.create_time,
       q.is_big_text,
       q.parent_id,
       q.que_version,
       q.casual,
       q.choise,
       q.answer,
       q.clob_casual,
       q.clob_choise,
       q.clob_answer,
       q.score,
       q.answer_time,
       q.source_code,
       q.source_code as sourceName,
       q.use_count,
       q.is_approved,
       q.is_avail,
       q.start_time,
       q.end_time,
       q.byinfor,
       q.update_time,
       q.update_user,
       (select dir_name from directorys where dir_id = q.lib_id) as lib_name,
       (select type_name from question_type where type_code = q.type_code) as type_name,
       (select diff_name
          from question_difficulty
         where diff_code = q.diff_code) as diff_name,
       (select qk_name
          from question_knowledge
         where knowledge_id = q.knowledge_id
           and type_code = 'K') as qk_name,
       (select ability_name
          from question_ability
         where ability_code = q.ability_code) as ability_name,
       secret
  from questions q
 where (end_time >= to_date('2016-09-20 09:54:03.375','YYYY-MM-DD HH24:MI:SS.FF3') or end_time is null)
   and is_avail = 'Y'
   and is_approved = 'Y'
   and parent_id = -1
   and q.que_id not in (select impl_que_id
                          from part_question
                         where partition_id in
                               (select pp.partition_id
                                  from paper_partition pp
                                 where pp.partition_exam_paper = 530501)
                           and impl_que_id is not null)
   and is_deleted = 'N'
   /* This line can be executed without commenting it out, and an error will be reported when commented out */
   /*and (exam_wh_id in (-11716325) or exam_wh_id = 11716325)*/
   and is_course = 'Y'
 order by update_time desc

The entire sql statement is used in such a time conversion place, and no problems have been found yet, and I will study it carefully after a while.
to_date('2016-09-20 09:32:34.382','yyyy-MM-dd HH24:mi:ss.ff3')



Is it because the following conditions have already filtered out the data, and the time condition has not Time to execute?