Before the burst of the most basic reading the contents of the book. But the main thing is closely related with their intercellular transmission of information this section. Then make a note of separate out.
The main information transmission between cells is mediated by extracellular signaling molecules, some extracellular signal molecules transmit information to distant cells, while other molecules pass information only to neighboring cells.
Signal transduction: an extracellular signaling molecules through specific binding to receptors on the cell membrane or intracellular, and converts the signal transmitted to the system after the appropriate intracellular, the cells respond to external signals.
Thesis in the use of receptors and ligands, but has not understood, just read the book and understand the significance of receptor ligands.
Receptor: receptor, specific proteins present in the cell membrane, or inside, can be specifically recognize and bind extracellular signaling molecules, thereby activating a series of biochemical reactions within cells, the cells produce a corresponding effect on external stimuli.
Ligand: ligand, including hormones, neurotransmitters, growth factors, certain drugs and toxins like. Receptor signal transduction system is critical, it is identified by ligand binding, signal transduction the entire trigger.
Japanese paper datasets Dehong Shanxi 2008 bioinformatics mentioned four receptors: nuclear receptor, G protein-coupled receptor, enzyme, ion channel. Use of these types of receptors that background, the latter three general membrane receptor, is embedded in the membrane glycoprotein of the extracellular domain that interacts with the ligand, the receptor immobilized on the cell membrane penetrating domain and plays the role of transmitting the signals of three parts constituting the intracellular domain. Ligands are generally not hydrophilic, peptide hormones can not be directly through the lipid bilayer membrane, growth factors and neurotransmitters.