This configuration would have been very simple, can I try a long time to thoroughly understand before has been using the AWS Simple Mail Service account to send a message, the result has been not issued, log Tip:
failed The to the send Email: SSL Connect error: error: 140770FC: SSL routines: SSL23_GET_SERVER_HELLO: unknown protocol
Later, I decided to try to use an external mailbox to see, it was also a beginning, and later found a clue here.
https://support.zabbix.com/browse/ZBX-11042
key point:
Then I put here later changed STARTTLS alert email sent successfully