Pharmaceutical excipients refer to auxiliary materials used in the pharmaceutical process to increase drug stability, improve taste, and increase absorption rate. There are many kinds of pharmaceutical excipients, and different drugs require different excipients. Therefore, it is particularly important for pharmaceutical companies to understand and choose the pharmaceutical excipients that suit them. This article will introduce how to use pharmaceutical excipient data query to help pharmaceutical companies better select pharmaceutical excipients.
1. The role of pharmaceutical excipients
Pharmaceutical excipients are an integral part of the pharmaceutical manufacturing process and they can perform many different functions. The following are some common pharmaceutical excipients and their functions:
1. Plasticizers: make solid medicines soft, easy to process, package and take, such as glycerin, propylene glycol, etc.
2. Stabilizers: prevent the deterioration and degradation of drugs, and prolong the shelf life of drugs, such as antioxidants, pH regulators, etc.
3. Binder: Form the drug powder into solid tablets or capsules, such as sodium carboxymethylcellulose, polyvinyl alcohol, etc.
4. Thickener: increase the viscosity of the drug, making the drug easier to take and store, such as sodium carboxymethyl cellulose, chitosan, etc.
5. Surfactants: improve the wettability and dispersibility of drugs, and increase the absorption rate of drugs, such as Tween, SLS, etc.
2. Importance of pharmaceutical excipient data query
When selecting pharmaceutical excipients, pharmaceutical companies need to consider many factors, such as the efficacy, safety, price, and production process of pharmaceutical excipients. These information can usually be obtained through data query of pharmaceutical excipients.
Pharmaceutical excipient data query refers to the process of using a certain database or search engine to obtain relevant pharmaceutical excipient information with keywords as input. This method can help pharmaceutical companies quickly obtain the required pharmaceutical excipient information, so as to make better decisions.
In addition, the data query of pharmaceutical excipients has the following advantages:
1. Saving time and cost: pharmaceutical companies do not need to spend a lot of time and money to investigate and collect information on pharmaceutical excipients, and can easily obtain the required information by querying the data of pharmaceutical excipients.
2. Improve the quality of decision-making: Pharmaceutical excipient data query can provide detailed and accurate information for pharmaceutical companies, helping pharmaceutical companies better understand the advantages and disadvantages of different pharmaceutical excipients, so as to make more informed decisions.
3. Improve production efficiency: pharmaceutical excipient data query can allow pharmaceutical companies to find suitable pharmaceutical excipients faster, thereby improving production efficiency and product quality.
3. Steps of pharmaceutical excipient data query method
- Inquire through the CDE website:
①Enter the official website of CDE (Center for Drug Evaluation, State Drug Administration).
②Find the "Information Disclosure" column on the home page, pull down, find "Auxiliary Package Registration Information", and click.
③In the opened interface, click "Registration Data of Pharmaceutical Excipients", enter the name of the pharmaceutical excipient or company name you want to find in the text box next to the query condition, and click "Query" to see the relevant data.
2. (Overseas data + download function) Query through Yaorong Cloud-excipient database group:
Yaorong Cloud-excipients database includes two databases [CDE raw materials, pharmaceutical excipients and pharmaceutical packaging materials registration information] and [FDA approved excipients], covering 44,000 pieces of data, adding the function of searching data to the original data function of CDE The filtering function, the expansion function of search results, and the data export and download function, etc., the support of these functions make the database widely used in the industry.
①Enter Yaorong Cloud Database --> Select Raw Materials --> Select Pharmaceutical Excipients Database
②Input 'target excipient' in the search box --> click the relevant 'filter condition' in the filter box --> finally click 'Search' to get the search result of the target excipient.
③ Click 'More Columns' or 'Export' in the lower right corner of the image above to export the target data.
Compared with CDE, Yaorong Cloud-excipient database is more suitable for the application of certain scenarios.
Pharmaceutical excipients are an integral part of the pharmaceutical process and they can perform many different functions. When pharmaceutical companies select pharmaceutical excipients, they need to consider many factors, such as the efficacy, safety, price, and production process of pharmaceutical excipients. Pharmaceutical excipient data query is one of the important means to help pharmaceutical companies better select pharmaceutical excipients. It can save time and cost, improve decision-making quality, and improve production efficiency. When querying the data of pharmaceutical excipients, it is necessary to pay attention to the accuracy, completeness, legal and safety issues of the data.