DOTA and its derivatives are one of the widely used new bifunctional chelating agents. DOTA and its derivatives not only have a mature synthetic process route, but also have good coordination and chelation capabilities. DOTA-polypeptide molecular probes are used as MRI comparisons. Agents, radionuclide targeted imaging agents and radiopharmaceuticals are widely used in the field of biomedicine. DOTA and its derivatives can be used to label and modify the following complexes:
DOTA functional chelating agent labeled polypeptide; p-NO2-Bn-DOTA; DOTA modified polypeptide chelating metal complex; p-NH2-Bn-DOTA; 111In-DOTA-PEG4-cRGDfk; p-NH2-Bn-DOTA-tetra( t-Bu-ester); 111In-DOTA-Lysine-cRGDfk; DOTA-tris (t-Bu ester); DOTA chelated lanthanide metal ion customization; DOTA-mono-NHS-tris (t-Bu ester), etc.
We have our own independent organic synthesis laboratory, which can independently produce and synthesize various macrocyclic ligands and chelating agents. We can synthesize macrocyclic ligands, bifunctional chelating agents, cyclodextrins, polyethers, cucurbiturils, and porphyrins. , Phthalocyanine, magnetic resonance reagents, reaction intermediates, etc.
Related list
CY3/CY5/CY7/CY7.5/ICG-DOTA
CY3/CY5/CY7/CY7.5/ICG-NOTA
DOTA-(Tyr3)-Octreotate
DOTA-111In-CY7
158Gd-ESMA
DOTA-Ec (RGDf K)
Gd-DOTA-4AmP
Gd-DOTP
Gd-DOTA-YHWYGYTPQNVI
Gd-DOTA-HYPYAHPTHPSW
DOTA functional chelating agent labeled peptide
DOTA modified polypeptide chelated metal complex
111In-DOTA-PEG4-cRGDfk
111In-DOTA-Lysine-cRGDfk
DOTA chelated lanthanide metal ion customization
Gd-DOTA-ACL
Ga-DOTA-Peptide
DOTA-RGD
The metal ions are independently selected from Cu, Fe, In, Tm, Yb, Y, Gd, Eu and lanthanides
dendrimer-Gd-DOTA
Gd-DOTA-PLGA
Gd-EDTA
DTPA-Gd
Gd-DOTA-polypeptide
Gd-DOTA-protein
Gd-DOTA-polysaccharide
Ga-DOTA-Tyr3-octreotide
Ga-DOTA-cRGD
Ga-DOTA-NIGHT
4-Aminobutyl-DOTA CAS:753421-63-5
p-NH?-Bn-DTPA CAS:102650-29-3
p-NH?-Bn-DTPA-penta (t-Bu ester) CAS:205956-41-0
p-SCN-Bn-DTPA CAS:102650-30-6
p-NH?-Bn-CHX-A-DTPA CAS:1105741-38-5
p-SCN-Bn-CHX-A-DTPA CAS:157380-45-5
DTPA-tetra (t-Bu ester) CAS:174267-71-1
Maleimido-mono-amide-DTPA CAS:2032239-75-9
p-NH?-Bn-PCTA CAS:2125661-64-3
p-SCN-Bn-PCTA CAS:949147-44-8
p-NH?-Bn-oxo-DO3A CAS:2125661-90-5
p-SCN-Bn-oxo-DO3A CAS:1370442-99-1
p-NH2-Bn-NOTA CAS:142131-37-1
p-SCN-Bn-NOTA CAS:147597-66-8
NO2A-Butyne-bis (t-Butyl ester) CAS:2125661-91-6
NOTA-bis (t-Bu ester) CAS: 1161415-28-6
Maleimido-mono-amide-NOTA CAS:
NO2A-Butyne CAS: 2089035-56-1
NO2A-Azide CAS: 2125661-92-7
NODAGA-tris (t -Bu ester) CAS: 438553-50-3
p-SCN-Bn-Deferoxamine CAS: 1222468-90-7
Deferoxamine-maleimide CAS: 1638156-31-6
Deferoxamine-DBCO
DOTA-Biotin-Sarcosine CAS: 180978-54-5
DO3A-Serotonin CAS: 2125661-93-8
DOTATATE CAS: 177943-89-4
DOTA CAS: 60239-18-1
DOTMA CAS: 148408-89-3
DOTAM CAS: 157599-02-5
CB-Cyclam CAS: 130701-19 -8
CB-TE2A CAS: 313229-90-2
DOTA-4AMP CAS: 254444-71-8
NOTE CAS: 56491-86-2
NOTP CAS: 83834-39-3
Tm-DOTA CAS: 78063-83-9
Gd-DOTA CAS: 72573-82-1
Tm-DOTP CAS: 30859-88-
Tm-DOTMA CAS: 2126179-30-2
Eu-DOTA-4Am CAS: 481668-57- 9
zzj 2021.3.23