cBioPortal (cBio Cancer Genomics Portal comprehensive analysis of cancer genes and clinical data)
• Official website: www.cbioportal.org/
• Introduction: The cBioPortal website integrates 126 tumor genome research data, including large tumor research projects such as TCGA and ICGC, covering 28,000 specimens. In addition, some samples also include phenotypic information such as clinical prognosis. . cBioPortal can be used directly without registration, and provides some small tools to facilitate users to generate article-level charts, which is very close to the needs of users.
• Research background
With the widespread application of microarray and high-throughput sequencing technologies, more and more genomics data have been accumulated in the field of tumor research, especially such as The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), etc. The launch and completion of the large-scale tumor genome sequencing project has accumulated a large amount of genomics data, which has so far occupied half of public databases such as NCBI, and has also produced a variety of databases to meet different research needs.
The flexible use of databases has become a basic skill that scientific researchers must master. For these databases, there are a lot of them. Many people are asking if there is a database that can get multiple results at once. A powerful tool for learning tumor genomics databases: cBioPortal website.
cBioPortal database usage
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- 1 Introduction to cBioPortal
- 2 Introduction to the main interface
- 3 Online analysis
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- 3.1 Choose various parameters
- 3.2 View test results (oncoprint)
- 3.3 View test results (Cancer Types Summary)
- 3.4 View test results (Mutual Exclusivity)
- 3.5 View test results (Plot)
- 3.5 View test results (Mutations)
- 3.5 View test results (Co-Expression)
- 3.5 View test results (Enrichments)
- 3.5 View test results (Network)
- 4 Setting of the function bar
- 5 Download of test results
1 Introduction to cBioPortal
2 Introduction to the main interface
3 Online analysis
3.1 Choose various parameters
3.2 View test results (oncoprint)
3.2.1 The function of the toolbar (1)
3.2.2 The function of the toolbar (2)
3.3 View test results (Cancer Types Summary)
3.4 View test results (Mutual Exclusivity)
3.5 View test results (Plot)
3.5 View test results (Mutations)
3.5 View test results (Co-Expression)
3.5 View test results (Enrichments)
3.5 View test results (Network)
4 Setting of the function bar
5 Download of test results
Reference article:
- View TCGA tumor data and analyze it with a graphical interface:
http://www.360doc.com/content/19/1224/13/68068867_881785176.shtml
https://blog.csdn.net/weixin_43569478/article/details/108079564 ?utm_medium=distribute.pc_relevant.none-task-blog-title-1&spm=1001.2101.3001.4242 - Tutorial for using cBioPortal database:
http://www.360doc.com/content/20/0502/21/45852776_909857256.shtml
https://blog.csdn.net/yjj18636810884/article/details/86612148 - Reference document: cBioPortal database
https://wenku.baidu.com/view/35e59bb076c66137ee0619d0.html