First, we need to add a reference to the namespace " using System.Text.RegularExpressions;" Let's take a string as an example: the code is as follows: string ss = " aaZ31 dd2f3 " ; string sss = ss.Replace ( " " , "" ); // Remove the spaces in the string ss string sss2 = Regex.Replace (ss, " [a-zA-Z] " , "" ); // Remove the English letters in the string ss MessageBox.Show (sss) ; // The dialog pop-up value is aaZ31dd2f3 MessageBox.Show (sss2); // The dialog pop-up value is 31 23 if (Regex.Matches (ss, " [a-zA-Z] ") .Count> 0 ) // If the number of captured letters is greater than zero { // there are English letters in the string } else // vice versa